Jadon Sancho, Phil Foden, Brahim Diaz and Dan Grimshaw were all present on Monday as the first team kicked off their schedule.
Goalkeeper Grimshaw, 19, could be set for a big opportunity to impress the manager on the tour to the United States.
“These are players that are extremely talented,” said chairman Khaldoon Al Mubarak in May.
“These are players who have a very good chance of making it to the first team.
“And these are players that if you ask Pep today he will tell you they can and will be first-team players at Manchester City.”