Arsenal are preparing to spend their first season outside of the Champions League for the first time in 20 years, after failing to secure a top-four finish.
The last time the Gunners experienced Europe’s second-tier club competition was 1999/2000 when they reached the final, but lost to Turkish side Galatasaray on penalties.
Arsene Wenger has never won a European trophy at Arsenal, so he will be desperate to make amends this season.
The winners receive an automatic Champions League place next season, which is certainly an added incentive for the Gunners.
Here is all you need to know about the draw which kicks off Arsenal’s potential journey to the final in Lyon next May – and the hardest group they could get.
When and where is the draw?
The draw begins today at 12:00pm UK time (13:00CET) at the Grimaldi Forum in Monaco. It will be streamed live on UEFA.com.
How will the draw work?
The 48 entrants are split into four seeding pots based on their club coefficients, with each of the eventual 12 groups to contain one team from each seeding tier.
The 22 play-off winners, the ten losing teams from the UEFA Champions League play-offs and the 16 sides entering at this stage make up the 48 clubs that go into the group stage draw at the Grimaldi Forum.
No team can play a club from their own association, with the exact draw procedure confirmed before the ceremony.
Who could Arsenal face?
Pot 2: Steaua Bucharest, Ludogorets Razgrad, BATE Borisov, Young Boys, Marseille, Real Sociedad, Maccabi Tel-Aviv, Lokomotiv Moscow, Austria Vienna, Hertha Berlin, Nice
Pot 3: Astana, Partizan Belgrade, Hoffenheim, Cologne, NK Rijeka, Vitoria Guimaraes, Atalanta, Zulte Waregem, Zorya Luhansk, Rosenborg, Sheriff Tiraspol, Hapoel Beer-Sheva
Pot 4: Apollon Limassol, Istanbul Basaksehir, Konyaspor, Vitesse Arnhem, Slavia Prague, Red Star Belgrade, Skenderbeu, FC Zlin, AEK Athens, FC Lugano, Vardar Skopje, Ostersunds
Who Arsenal cannot face
Pot 1: Zenit St. Petersburg, Lyon, Dynamo Kiev, Villarreal, Athletic Bilbao, Lazio, AC Milan, Viktoria Plzen, FC Salzburg, FC Copenhagen, Braga
* Teams from the same country cannot face each other in the group stage
Group of death
Arsenal, Marseille, Hoffenheim, Istanbul Basaksehir
When are the group stage games?
Matchday one: 14 September
Matchday two: 28 September
Matchday three: 19 October
Matchday four: 2 November
Matchday five: 23 November
Matchday six: 7 December
What comes next?
The top two in the 12 UEFA Europa League groups will join the eight third-placed sides from the UEFA Champions League groups in the UEFA Europa League round of 32 draw, which takes place in Nyon on 11 December at 13:00CET.